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Most anal cancers (80) are diagnosed in people who are over age 60. However, after age 50, anal cancer is slightly more common in women. Anal cancer is a rare form of cancer that affects the tissues of the anus. We explain what you need to know about its causes and how its diagnosed. Is experiencing a dramatic and concerning rise in the rate of new anal cancer cases and deaths, particularly among young black men and elderly women. Anal pap smears similar to those used in cervical cancer screening have been studied for early detection of anal cancer in high-risk individuals. In 2011, an hiv clinic implemented a program to enhance access to anal cancer screening for hiv-positive men. Nurse practitioners perform anal papanicolaou screening, and men with abnormal results receive further evaluation with high-resolution anoscopy. The program has helped identify many precancerous growths, allowing them to be safely removed. Who does anal cancer affect? The risk of anal cancer is higher in women than in men. The general risk of getting anal cancer is about 1 in 500-600 people. What are the risk factors for anal cancer? The term risk factor refers to a thing that makes it more likely that you will get a disease. Anal cancer is cancer that arises in the anus, the end of the intestinal tract where stool (feces) exits the body. The cancer can begin either in the lining of the anus or in the skin surrounding the anus. Anal cancer is different from colon or rectal cancer, which arises in the other parts of the large intestine. Risk factors for developing anal cancer include infection with certain types of. Anal cancer is of growing concern among people living with hiv. In the general population, anal cancer is considered rare, about two per 100,000 people (2016 data). However, in men who have sex with men (msm), the incidence climbs to as high as 144 cases per 100,000. The outlook for anal cancer depends on how advanced the condition is when its diagnosed. Compared with many other types of cancer, the outlook for anal cancer is generally better because treatment is often very effective.